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KMID : 0351219930250020167
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Korean Journal of Infectious Diseases
1993 Volume.25 No. 2 p.167 ~ p.176
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Disseminated Tuberculosis and Aspergillosis in a Patient with Lupus Nephritis Undergoing Steroid 'Pulse' Therapy : The Clinical and Autopsy Findings
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이준성
백경란/오명돈/김성권/최강원/박원서/지제근/김용일
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Abstract
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Although steroids have been used for a long time in the treatment of systemic lupus erythmatosus(SLE), steroids may result in a major defect in host defences and increased prevalence of a wide variety of infection.
Steroid 'Pulse' therapy has been advocated for effective management or certain circumstance such as lupus nephritis, rapidly progressive glomerulonephritis, minimal change nephrotic syndrom but the use of high dose steroid is a problem because of
the
danger of mycobacterial and fungal infection.
We report the clinical and pathological findings of a lupus nephritis patient with fulminant course of disseminated tuberculosis and aspergillosis after steroid 'Pulse' therapy.
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